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Chronic alternate-day fasting results in reduced diastolic compliance and diminished systolic reserve in rats
A nutrient-dense diet supplying methylation cofactors (folate, betaine, vitamin B12, vitamin B2, etc.) is foundational
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Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension
These catechol estrogen metabolites can be further changed by the COMT (catechol-O-methyltransferase) enzyme or through glucuronidation ( UGT genes)
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