In this study, the radical scavenging activities of Cys and GSH were confirmed (Table 1) and showed that they inhibited the accumulation of ROS and MDA by upregulating the expression of antioxidant enzymes in ethanol-treated ICR mice and HepG2 cells (Figure 4 and Figure 7)
Keynes RG, Karchevskaya A, Riddall D, Griffiths CH, Bellamy TC, Chan AWE, Selwood DL, Garthwaite J (2019) N 10 -carbonyl-substituted phenothiazines inhibiting lipid peroxidation and associated nitric oxide consumption powerfully protect brain tissue against oxidative stress
Caution: Consult a health care practitioner prior to use if you are pregnant or breastfeeding
Selective mitochondrial glutathione depletion by ethanol enhances acetaminophen toxicity in rat liver
Inflammopharmacology 30:811820 Almezgagi M, Zhang Y, Hezam K, Shamsan E, Gamah M, Al-shaebi F, Abbas AB, Shoaib M, Saif B, Han Y, Jia R, Zhang W (2020) Diacerein: recent insight into pharmacological activities and molecular pathways