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It upregulates the expression of anti-inflammatory genes, including NF-BIA , MAP3K8 , and TLR5 , while concurrently downregulating pro-inflammatory genes such as TNFSF6 , TNF- , and nuclear factor-B ( NF-B ) [36,37,38,39]

In nucleated cells, their functions are not limited to apoptosis, and caspases have been demonstrated to be involved in the regulation of multiple RCDs and related mechanisms, including pyroptosis (caspase-1), necroptosis (caspase-8), mitotic catastrophe (caspase-2), and regulation of inflammation [4]

Identify the thiol (-SH) groups in the glutathione molecule that will form a disulfide bond (-S-S-) in the oxidized GSSG molecule

DOI: 10.1186/1471-2202-9-S2-S15

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