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Participants in key studies achieved average weight reductions that significantly exceeded those seen with placebo, alongside improvements in cardiometabolic markers

FDA Press Release on First Treatment for Menkes Disease Rare Disease: FDA Expands Treatment Approval for Gaucher Disease The FDA expanded the approval of Sanofis Cerezyme (imiglucerase) intravenous infusion enzyme replacement therapy to treat non-neurological symptoms in patients with Type 3 Gaucher disease, which is the rarest and most serious type

[177] [178] However, large doses of amphetamine may indirectly cause dopaminergic neurotoxicity as a result of hyperpyrexia, the excessive formation of reactive oxygen species, and increased autoxidation of dopamine

and found that AFib patients with obesity who were treated with a diabetes-managing dose of GLP-1s experienced fewer AFib-related events

No studies were added via Trim and Fill, confirming symmetry in the funnel plot