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Given that YAP is a transcriptional co-activator known to translocate into the nucleus in response to ECM stiffening in various cell types, including melanoma cells (Miskolczi et al, 2018), and that YAP may serve as a potential MITF partner in uveal melanoma cells (Barbosa et al, 2023), we wondered whether YAP could be associated with the observed ECM-dependent MC phenotypes

Small changes compound over time to create big improvements in your antioxidant defenses

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However, conclusive evidence regarding their relative effectiveness in preserving ovarian reserve is lacking, and the precise molecular mechanisms remain to be fully elucidated

doi: 10.1111/j.1360-0443.2012.04054.x