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Multiple independent studies have reported that PYY-/- mice exhibit hyperinsulinemia and are prone to developing obesity and insulin resistance during aging or under long-term high-fat diet challenges (138, 139)
In an interventional study, it was shown that L-carnitine supplementation with a dose of 3 g/day for 12 weeks significantly reduced FBG, but its effects on HbA1c reduction were not significant in diabetic patients (17), the results of this study confirm our findings in terms of reducing FBG, but from the point of view of the effect on HbA1c, it does not confirm the results of our study
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