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Reduced penetration in turn provides more time for detoxification by facilitating the action of metabolic enzymes

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Risk Band 2 types like HPV 33/58, 52, 45 also carry significant risk but may behave differently and less agressively than Risk Band 1 subtypes while the remaining 7 strains in Risk Band 3 are less common causes of high grade cervical disease and can often be managed with observation alone