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This improvement was achieved by ROS levels and apoptosis, increasing mitochondrial membrane potential, optimizing mitochondrial distribution, and upregulating genes associated with oocyte quality (Zhang et al., 2025)

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Certain populations need to inject B12 in larger doses to maintain baseline health: Individuals with pernicious anemia are initially injected with 100 mcg daily for one week, followed by 100 mcg every other day for 3-4 weeks