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While hyperhomocysteinemia may increase the risk of cognitive impairment and age-related neurodegenerative disease (e.g., Alzheimers disease), it is not clear whether vitamin B 12 deficiency contributes to the risk of dementia in the elderly

Patients on these combination regimens may require dose adjustments of concurrent diabetes medications to prevent low blood sugar episodes

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Depression and risk of mortality in people with diabetes mellitus: a systematic review and meta-analysis