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GLP-1 receptor agonists are a class of medications that mimic a natural hormone in the body, which helps regulate blood sugar, slows digestion, and signals feelings of fullness to the brain

Concentration-dependent studies showed both lead compounds achieved potent KRAS G12C degradation in NCI-H23 cells (DC = 2 nM), with DJX-A-KM demonstrating superior maximum degradation ( D max = 98% vs

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Among these inhibitors, a mild, stable, safe and effective compound is sought from natural extracts as a raw material for the development of skin-whitening and skin care products