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To this end, after ACTL6A expression levels were detected (Fig

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Glutamine serves as a critical substrate for -ketoglutarate (-KG) production, which is an essential cofactor for several enzymes involved in epigenetic modifications, e.g., Jumonji C (JmjC)-containing histone lysine demethylases (KDM) and DNA demethylases teneleven translocation (TET) enzymes [90,91]