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[ref] Related article: Epstein-Barr virus genetic susceptibility Non-viral root causes of ME/CFS: Its important to note that not all ME/CFS cases can be traced to a viral infection

An in-depth mechanistic study has shown that activation of the BDNF signaling pathway significantly increases protein levels of neurexin- and neuroligin 1 and synaptic plasticity in the hippocampus, possibly involving TrkB/PI3k/AKT/mTOR in this process [54]

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Theres no downtime associated with the treatment