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Creatine's primary benefit is increasing muscle strength and retention during a calorie deficit

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A thorough medical evaluation, including blood work to check IGF-1 levels and overall hormone status, is the safest first step before starting therapy

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41,50 In patients in whom surgical excision is not feasible, cosmetic benefit may be obtained from procedures such as curettage, dermabrasion, and ablative laser therapy (eg, carbon dioxide or erbium:YAG, sometimes combined with pigment-directed lasers), especially when done during the newborn period when there is a lower risk of scarring and active melanocytes are concentrated in the upper dermis

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