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Abstract Recent retrospective cohort studies showed that use of glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) increased the incident risk of diabetic retinopathy and nonarteritic anterior ischemic optic neuropathy (NAION)
As a result of its ability to inhibit the expression of transcription factors and pro-inflammatory cytokines such as TNF-, IL-1, IL-6, IL-8, IL-12, IL-1, and monocyte chemoattractant protein-1 (MCP-1), curcumin has demonstrated anti-inflammatory properties ( Supplementary Table 1 )
2.Stimulated Protein Synthesis Creatine upregulates myogenic transcription factors and satellite cell activity, amplifying anabolic signaling in muscle fibers
Los estudios en animales muestran que la L-carnitina tiene efectos cardioprotectores al prevenir la miopata del msculo esqueltico y puede mejorar los patrones metablicos del miocardio, reducir la necrosis, disminuir el tamao del infarto enzimtico y preservar la funcin ventricular izquierda