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Genes increasing in expression with increasing emphysematous destruction included those involved in inflammation, such as the B-cell receptor signaling pathway, while genes decreasing in expression were enriched in tissue repair processes, including the transforming growth factor beta (TGF) pathway, actin organization, and integrin signaling

Human safety and efficacy are not established, as preclinical results do not predict human outcomes

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Its ability to regulate actin, a critical component of cell structure and movement, makes it uniquely suited for studies involving injury recovery and tissue remodeling

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