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Although our study shows that federal policy change can help increase access to GLP-1s for heart disease, we still have a long way to go to ensure that patients can access and afford these medications as their clinical indications keep expanding, said first author Christopher Scannell, a nonresident scholar at the USC Schaeffer Institute and senior research associate at the USC Mann School of Pharmacy and Pharmaceutical Sciences

The data on insulin secretion, insulin sensitivity, and glucose homeostasis were confirmed in the phase II clinical study (clinical trials registration number NCT03131687) (62)

In plain terms, it is the process in which healthy tissue cells turn into rigid, scar-producing cells, which in turn causes heart stiffness or cardiac fibrosis

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Additional variables included overweight and obesity status using ICD-10-CM codes E65E68 and granular body mass index (BMI) categories defined by Z68.27 through Z68.42