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They work by mimicking the natural hormone GLP-1, which plays a role in regulating appetite and digestion

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Blood was collected in EDTA-coated microvette tubes, chilled on ice and centrifuged at 3,000 g and 4 C for 10 min

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Serine pools are further expanded by the de novo serine synthesis pathway, which metabolizes the glycolysis product 3-PG into serine and generate NADH and KG byproducts