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The normal functions of the body typically destabilize any antioxidant, but with glutathione, it is important to have a strong ratio of reduced that is, active glutathione (GSH) to oxidized glutathione (GSSG)

Lysophosphatidylcholine acyltransferase 3 (LPCAT3) works synergistically with ACSL4, responsible for incorporating the PUFA-CoA activated by ACSL4 into membrane phospholipids, completing membrane remodeling

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Peer review Peer review information Nature Communications thanks David Vilchez and the other, anonymous, reviewer(s) for their contribution to the peer review of this work