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Initial effectiveness data for APHD-012 is expected by the end of 2024 following the completion of phase 2 trials

In the Longitudinal Assessment of Bariatric Surgery (LABS) study by Courcoulas et al

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Tryptophan-derived metabolites, such as indole and its derivatives, influence bacterial biofilm formation and pathogenicity through AhR-mediated pathways, concurrently influencing host immunological responses 47

Signal characteristics include : T1: 75% are isointense, 25% are hypointense