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Researchers theorize that asthma may be due to either inappropriate mast cell activation or that the mast cells are hypersecretory.[ref][ref] One study sums up that mast cells release preformed mediators including chymase, tryptase, and histamine and de novo synthesized mediators such as PGD2, LTC4, and LTE4 in addition of cytokines mainly TGF1, TSLP, IL-33, IL-4, and IL-13 participate in the pathogenesis of asthma.[ref] Related article : Asthma: understanding the genetics and underlying causes Osteoarthritis: Mast cells as a causative factor Osteoarthritis, the most common form of arthritis, is caused by inflammation and degeneration of the joint tissue

Results Experimental results Vitamin B 12 and GSH are uncorrelated in type 2 diabetic patients We analyzed vitamin B 12 levels and blood GSH concentrations in Indian diabetic patients and control subjects

Gibson RJ, Keefe DM

Clostridium butyricum pretreatment attenuates cerebral ischemia/reperfusion injury in mice via anti-oxidation and anti-apoptosis

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