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Bixin protects mice against ventilation-induced lung injury in an NRF2-dependent manner

Mechanisms Under Investigation Gene expression and extracellular matrix signaling

Sterile water for injection is prepared by using water purification system

After treated 4 days, all rats were observed under slit lamp microscope, the morphology of cornea and fundus oculi were detected by a small animal optical coherence tomography (OCT) system (Optoprobe, OPIMG, UK) and a small animals fundus imaging system (Optoprobe, OPIMG-L, UK)

Yet products commonly contain 1% or higher, delivering concentrations millions of times greater than the minimum effective dose