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Magnesium glycinate doesnt draw water into the large intestine like magnesium oxide, as its bound with two glycine molecules, leaving no room for water to attach, as it would if you took magnesium oxide

A researcher conducting a 12-week protocol at 500mcg total dose five days per week needs 60 doses totalmeaning a 10mg vial yields insufficient doses (only 20), requiring three vials over the study period, while two 15mg vials would suffice with a dose buffer

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Moreover, adequate safety margins were observed in repeat-dose rat and monkey toxicology studies, which supported advancing PF-06882961 to human clinical studies