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Combination therapies Combination therapies that work via two mechanistically distinct targets to integrate immune modulation with a beta cell-specific component have been suggested [139,140,141] and encouraged [142]

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Safety and Side Effects Like all therapeutic interventions, GLP-1 agonists come with their set of side effects

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These results suggest that mild to moderate hyperglycemia is required for the insulinotropic effect of GIP in nondiabetic subjects, acting as a mechanism to prevent reactive hypoglycemia following the consumption of fatty foods