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This variation is largely influenced by genetic differences in the enzymes responsible for its production and regeneration (1)

469-478 [online] Available at: McGrogan, L., Mackinder, M., Stefanowicz, F., Aroutiounova, M., Catchpole, A., Wadsworth, J., Buchanan, E., Cardigan, T., Duncan, H., Hansen, R., Rissell, R.K., Edwards, C.A., Talwar, D., McGrogan, P

Methods Lipid peroxidation and antioxidant enzymes activity were estimated using spectrophotometric methods

Glutathione protects cells from oxidative damage , including byproducts created during energy production

Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice