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When combined with anti-cytotoxic T-lymphocyte-associated protein 4 (anti-CTLA-4) therapy, it significantly increased the proportion of cytotoxic T cells, while reducing Foxp3 Treg cells to half the level observed with D/B/CQ@ZIF-8@CS monotherapy

10.1016/j.bbadis.2019.165552 4 Al-SalamS.JagadeeshG

Microbiome-directed probiotic interventions have shown promise in preclinical and clinical studies, ameliorating UC through multiple mechanisms, including anti-inflammatory activity, epithelial barrier restoration, and remodeling of the intestinal microbiota

Age plays a role in response timelines as well

Plant Physiol 141: 397403.