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Shirali, A

Globally, EBV causes more than 200,000 cancers annually, including endemic Burkitts lymphoma, Hodgkins lymphoma, non-Hodgkins lymphoma, central nervous system (CNS) lymphoma in patients with late-stage HIV infection, posttransplant lymphoproliferative disease (PTLD), nasopharyngeal carcinoma, and gastric carcinoma 5

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Furthermore, inhibiting iron response element binding protein 2 (IREB2) using shRNA changes the expression of various iron genes (e.g., TRFC, FTH1, and FTL), affecting iron absorption, metabolism, and storage (80, 81)

Nov 1 2020;276:297-304