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Pharmacokinetics (PK) The PK profile demonstrated a dose-proportional increase in maximum concentration (Cmax) and area under the curve (AUC) supporting once-weekly dosing with a mean half-life of approximately 150 hours

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Patients often consume: Smaller meals Fewer solid foods More frequent grazing. Protein shakes or meal replacements

The relevant OD value at 450nm for stopping the staining is between 2.0 - 2.5