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The peptides antioxidant properties appear to work through multiple pathways: direct quenching of lipid peroxidation products, activation of antioxidant enzymes like SOD, and modulation of inflammatory gene expression (Pickart et al., 2015)

While no studies have indicated a beneficial effect of liraglutide or semaglutide in Parkinson's Disease, a study with exenatide has indicated that long-acting GLP-1RAs may prevent deterioration in motor symptoms in patients with the condition (209), and the suggested mechanism may be a microglia-initiated effect to prevent astrocytes from forming a toxic phenotype (121, 210)

Most of our patients report noticeable results within 4 weeks of beginning treatment

Shoulders MD, Raines RT

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