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Physiological factors such as Ca 2+ , 25(OH)VD, 1,25(OH) 2 VD, and VDBP regulate the expression of VDR [24]

In recent years, increasing evidence has suggested that traditional Chinese medicine and its active monomers can inhibit hepatocyte ferroptosis, exerting a protective effect against alcohol-induced liver injury

355,356,357 According to most related studies, osteoclasts and osteoblasts are indispensable for bone remodeling, and bone resorption and bone formation are mediated by osteoclasts and osteoblasts, respectively

Insulin primarily enters the brain via selective, saturable transport across the blood-brain barrier (BBB) 373,374,375 Peripherally produced insulin can also be actively transported into the brain via an endocytic-exocytic mechanism

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