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Another study [44] with uremic patients with some degree of muscular atrophy, reports that 24-week treatment with l-carnitine (2 g IV at the end of hemodialysis, or in dialysis solution, or per os twice daily) leads to an increase of about 7% in the diameter of type I and type IIa fibers, as well as to a reduction in atrophic fibers

However, this approach demands larger sample sizes, higher sequencing costs, and sufficient material from each animalchallenges that intensify with multiple omics layers [25]

Therefore, ALC may be a potential cholesterol-lowering agent

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