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This hormone, glucagon-like peptide-1, plays a key role in regulating your appetite, digestion, and blood sugar levels

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Participants were required to have a BMI between 28 and 38 kg/m 2 , to have an HbA1c concentration between 6.5 and 9%

A clinical hierarchy: dont stack until youve earned the right to stack Before we even talk combinations, an evidence-led clinic typically wants these foundations in place: Diagnosis clarity: Obesity phenotype, insulin resistance, prediabetes/T2D, dyslipidemia, sleep apnea risk, NAFLD risk Baseline labs: A1c, fasting glucose/insulin (or at least glucose), lipids, CMP, CBC