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6 Conclusion In conclusion, oxidative stress is involved in AD pathophysiology, therefore there is a strong preclinical rationale to incorporate antioxidative agents, as adjuvant treatment, in the AD pharmacopeia

The main limitation is that reduced GSH is vulnerable to stomach acid and digestive enzymes, which break it down before absorption

Briefly, the subsequent administration of DAPA after the experimental induction of hyperthyroidism had a tremendous impact on both heart and lung tissues

.,KimH-S,QuonMJKimJ-ANew insights into the mechanisms of polyphenols beyond antioxidant properties

6 Limitations Despite the comprehensive delineation of glycyrrhizins multifaceted mechanisms in preclinical models, it is imperative to acknowledge that most of these pathways have been primarily characterized in vitro and animal studies