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Composite endpoints that include metabolic endpoints, validated psychological measures such as the PHQ-9 for depression, BES or measures of quality of life can better reflect improvements in both physical and mental health [41]

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Employing peat filtration and utilising reverse osmosis (RO) water can also prove beneficial in maintaining optimal conditions

GSH, an endogenous antioxidant synthesized from different amino acids including glycine, cysteine, and glutamate, effectively inhibits oxidative stress-related damage and altered ROS production level (30, 31)