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In the LEADER study with liraglutide, in patients with CKD stage 3, this cardiovascular benefit proved to be greater.58 Although the cardiovascular safety studies were not powered to detect differences in individual components of MACE, some differences between studies were seen in these individual components

Oral administration of high-dose vitamin B 12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms

Rubino, D., et al., Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial

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