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Transcriptomic analysis of the liver of pediatric patients revealed no changes in GR mRNA expression as compared to the liver of healthy controls (Desai et al

(54), the supplementation of CoQ10 and -lipoic acid inhibited cisplatin-induced nephrotoxicity

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Despite these limitations, WES continues to offer one of the most favorable costbenefit outcomes, offering almost the same percentage of diagnostic yield as Whole Genome Sequencing (WGS), but with and substantially lower bioinformatics workload (Nurchis et al., 2023)

Supplementation of cystine suppressed the ISR as evidenced by the reduction of phospho-eIF2 (S51) and ATF4, but rapamycin treatment had no discernible effect (Fig