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These coordinated effects collectively promote hepatic metabolic homeostasis restoration
Before prescribing, clinicians should confirm appropriate indicationseither inadequately controlled type 2 diabetes or obesity with BMI 30 kg/m (or 27 kg/m with weight-related comorbidities such as hypertension or dyslipidemia)
In addition, there is evidence that GLP-1 has effects on adipose tissue and skeletal muscle that are extra-pancreatic 23,24
For prescription medications, donation services typically assess: The underlying condition being treatedwhether it affects donor fitness Medication stability how long the donor has been on treatment without adverse effects Potential side effects that might be exacerbated by donation (such as dizziness or dehydration) Overall health status including minimum weight (50 kg), haemoglobin levels, blood pressure, and venous access Many common medications are acceptable for donation, including most antihypertensives, statins, and thyroid replacement therapy , provided the underlying condition is well-controlled
The change may take effect as early as May 29, pending product availability
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