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Furthermore, as explicitly noted in trials like Santilli et al

4 The LEGACY study tracked what happens when this is reversed

A total of 170 patients participated in a 12-week, randomized, double-blind, placebo-controlled trial conducted to evaluate the efficacy and safety of saxagliptin 2.5 mg once daily compared with placebo in patients with type 2 diabetes mellitus and moderate (n=90) or severe (n=41) renal impairment or ESRD (n=39)

This alteration in AMPA receptor dynamics can further contribute to the impairment of LTP, as the activation of AMPA receptors is essential for the stabilization of LTP following its induction (Gerace et al

Read more Learn tips to manage heartburn while using GLP-1 medications safely