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They used electronic health record data from OneFlorida+ Clinical Research Consortium, a health care data repository, from January 2014 to June 2023

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Decreased cognitive function, fatigue, lethargy, fainting, depression or irritability, headache, balance issues, and other symptoms are all possible side effects of B12 deficiency

However, a drawback of these medicines has been the necessity for administration by subcutaneous injection, which limits patient utilization and may reduce opportunities for fixed-dose combination treatments with other small-molecule drugs