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Studies indicate that NAFLD pathogenesis is closely associated with insulin resistance, that leads to increase in free fatty acid flux to the liver, oxidative stress, and inflammatory signaling through toll-like receptors (TLRs) [175]
Studies show that B12 has a role in keeping nerves healthy and supporting brain function when there is a deficiency
Chronic Oxidative Stress (Depletes Glutathione Faster Than Its Made) Anything that increases free radical production depletes glutathione: Chronic inflammation (autoimmune diseases, obesity, metabolic syndrome) Environmental toxins (air pollution, pesticides, heavy metals) Alcohol consumption (glutathione is rapidly depleted in liver detoxification) Poor diet (high in processed foods, seed oils, sugar) Intense exercise (without adequate recovery) When oxidative stress exceeds your bodys capacity to recycle GSSG back to GSH, levels drop [4]
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