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[PubMed] [Google Scholar] 174.Jefferies WA, Brandon MR, Hunt SV, et al

The deletion of PNPLA2 in adipocytes resulted in reduced PPAR activity and expression of target genes, including lower UCP1 protein levels and when exposed to cold, mice were cold sensitive (140)

[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Cohen-Adad J, El Mendili MM, Lehricy S, Pradat PF, Blancho S, Rossignol S, et al

Phosphorylation of Akt leads to activation of TOR, a molecular sensor of metabolism and cellular homeostasis (Wullschleger et al., 6B)