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If you're managing nausea, vomiting, or diarrhea at your current dose and schedule, taking a dose early will make those symptoms worse

In these people, blood tests reveal thyroid abnormalities (elevated TSH with normal T4 and T3) and can identify the presence of thyroid antibodies, but they are either asymptomatic or the symptoms have not been associated with possible hypothyroidism

So far the research is reassuring, however these are all rare, so its unlikely we will know if there is any significant increase for some years to come

Weight loss surgery may be your next step or next option to consider on your journey

Osteoclasts are derived from haematopoietic stem cells (HSCs), specifically from the monocyte/macrophage lineage ( Figure 1 )