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Clinical trials consistently show reductions in total caloric consumption in patients treated with semaglutide and tirzepatide. When energy intake decreases substantially, micronutrient intake may also decline unless food quality remains high

Nausea and vomiting occur more frequently in the first weeks but typically resolve as the body adapts

Split into two 0.55ml injections (5.5mg each) administered 12 hours apart to maintain stable plasma levels throughout the loading phase

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