diabetes and semaglutide (Ozempic/Wegovy) shows 3-year efficacy for blood sugar control weight loss Peptide of the Week: Semaglutide

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The combination of basal insulin with GLP-1 RA results in greater glycaemic lowering efficacy than the mono-components, with less weight gain and lower rates of hypoglycaemia than with intensified insulin regimens, and better gastrointestinal tolerability than with GLP-1 RA alone [214, 215]

Zalfa C, Paust S

Potential Side Effects of Semaglutide Although Semaglutide is generally well-tolerated, it may cause side effects such as nausea, diarrhea, and constipation, particularly during the initial phase of treatment

Patients who continue semaglutide therapy maintain 80-90% of their weight loss even after 2-3 years, along with sustained improvements in energy, mobility, and blood sugar control