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RhoA, Rac1, and Cdc42 were initially found to be required in the growth factor-induced formation of focal adhesions and actin stress fibers (contractile actin and myosin filaments), membrane ruffles/lamellipodia (meshwork of newly polymerized actin filaments), and filopodia (actin-rich and finger-like membrane extension structures) in fibroblast cells (Ridley et al., 1992

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Clin Endocrinol 91:892898 Krysiak R, Gdula-Dymek A, Bednarska-Czerwiska A, Okopie B (2007) Growth hormone therapy in children and adults

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