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In adults, taking approximately 4 grams in a 24-hour period about six extra-strength 650 mg tabletscan damage the liver

doi:10.1111/j.1365-313X.2007.03280.x

These effects were achieved under reduced activation of noncanonical signaling pathways including receptor internalization and -arrestin recruitment, an initially surprising observation as these have previously been linked to increased GLP-1R responses when measured acutely 10,14,36

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Safely dispose of the patch as directed above and use a new patch