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Bacteroidetes Bacteroidetes, as foundational Gram-negative anaerobic commensals in the mammalian intestinal ecosystem, play therapeutic and regulatory roles by strengthening the intestinal mucosal barrier, maintaining immunomodulatory balance, and optimizing metabolism [155]

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2008) investigated the pharmacokinetics of 2, 5, 10, and 15 g of citrulline within eight healthy volunteers and demonstrated that larger doses could be more appropriate