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a method of treating an obesity-related complication described herein results in a decrease in blood levels of IL-1 of at least about 10%, at least about 20%, at least about 30%, at least about 40%, at least about 50%, at least about 60%, at least about 70%, at least about 80% or at least about 90% compared to blood levels of IL-1 prior to treatment

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The deadline for all parties to finish expert depositions is March 27, 2026