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British Medical Bulletin , 1999, 55:578-92

Short-term placebo-controlled studies do not show a consistent effect of antibiotic-induced disruptions of the gut microbiome on body weight and insulin sensitivity in humans but suggest an individual-specific or subgroup-specific response

All three receptor subtypes (muscarinic acetylcholine M3, bradykinin B2, and adenosine A 2a ) are coupled to G q -type G-proteins that exert their effects through activation of PLC