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If your levels were already healthy, a single shot tops you off, and the noticeable effects fade sooner

The symptoms of vitamin B12 deficiency may be reversible in some cases and permanent in others

doi:10.1038/nrgastro.2009.125

Because B12 shots are administered intramuscularly, they bypass the digestive system, allowing the body to absorb a much larger amount of B12 that would otherwise be lost during digestion

It is the pharmacological equivalent of pointing a targeted spotlight at liver fat specifically and saying "burn this." For anyone concerned about metabolic health beyond simple weight management, this liver fat data may be the single most important differentiator between the two compounds