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Elevated Growth/differentiation factor 15 (GDF15) level in serum and increased GDF15 expression in cancer tissues are reported in patients with various cancers, and associated with the poor prognosis of the patients (Welsh et al., 2001

Supplementation with soluble dietary fiber has been shown to increase the abundance of beneficial bacteria while significantly reducing TMA and TMAO metabolism in red meat-fed mice (by 40.6% and 62.6%, respectively)

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Like many therapeutic peptides, it may require daily (or near-daily) administration, as in the previously referenced mouse and rabbit studies.12 17 Moreover, as a preventive or a drug for managing chronic health conditions, treatment ought to be ongoing and may involve periodic breaks in dosing (cycling), which is also common with many therapeutic peptides